Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24089963 | 1.00 | MAPT (0.43) | MAPTHDAC1HDAC8HDAC6CA12 | |
| SCHEMBL24090104 | 0.93 | USP2 (0.44) | MAPTHDAC1HDAC8HDAC6PDE7A | |
| SCHEMBL24089982 | 0.90 | JUN (0.45) | MAPT | |
| SCHEMBL24089969 | 0.88 | IDO1 (0.42) | MAPTHDAC1HDAC8HDAC6EGFR | |
| SCHEMBL29623172 | 0.87 | TDO2 (0.44) | HDAC1HDAC8HDAC6HDAC2 | |
| SCHEMBL29623225 | 0.87 | KDM4E (0.44) | — | |
| SCHEMBL24090107 | 0.87 | TDO2 (0.44) | HDAC1HDAC8HDAC6HDAC2 | |
| SCHEMBL23045330 | 0.87 | KDM4E (0.44) | — | |
| SCHEMBL24089985 | 0.86 | KDM1A (0.42) | MAPTHDAC6 | |
| SCHEMBL24090010 | 0.86 | USP2 (0.52) | MAPTPDE7AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | claimed |
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |