Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | TDO2 | P48775 | 3/20 | 0.55 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23065082 | 1.00 | IDO1 (0.55) | IDO1TDO2IDO2KCNH2ALDH1A1 | |
| SCHEMBL23065101 | 0.92 | MEN1 (0.48) | IDO1TDO2IDO2KCNH2ALDH1A1 | |
| SCHEMBL29623188 | 0.91 | MEN1 (0.52) | IDO1TDO2IDO2KCNH2ALDH1A1 | |
| SCHEMBL23065098 | 0.91 | MEN1 (0.52) | IDO1TDO2IDO2KCNH2ALDH1A1 | |
| SCHEMBL24089977 | 0.90 | KMT2A (0.47) | IDO1TDO2IDO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29623222 | 0.90 | KMT2A (0.47) | IDO1TDO2IDO2ALDH1A1SMN1; SMN2 | |
| SCHEMBL24089967 | 0.86 | TDO2 (0.41) | IDO1TDO2IDO2HTR7JAK2 | |
| SCHEMBL24089899 | 0.86 | HTR7 (0.41) | IDO1TDO2IDO2ALDH1A1MEN1 | |
| SCHEMBL24089983 | 0.86 | HTR7 (0.41) | IDO1TDO2IDO2KCNH2HTR7 | |
| SCHEMBL23065077 | 0.85 | HTR7 (0.42) | IDO1TDO2IDO2SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | claimed |
| CN-114650986-A | 2-aminoquinazolinone derivatives | 住友制药株式会社 | 2022-06-21 | — | — | CN | disclosed |