Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546439 | 0.80 | NPSR1 (0.53) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29603301 | 0.80 | NPSR1 (0.53) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL14252748 | 0.78 | MAOB (0.46) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10543967 | 0.78 | MAOB (0.40) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL3891773 | 0.77 | MAOB (0.47) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL10877632 | 0.76 | MAOB (0.48) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL29623436 | 0.75 | AR (0.47) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL31360387 | 0.75 | NPC1 (0.47) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL17608977 | 0.74 | MAOB (0.44) | SLC6A4MAOB | |
| SCHEMBL29623526 | 0.74 | CYP1A2 (0.45) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790149-B | Phenoxytriazoles | 豪夫迈·罗氏有限公司 | 2022-05-17 | — | — | CN | disclosed |