Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9546439 | 1.00 | NPSR1 (0.53) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL1813853 | 0.91 | TEAD1 (0.51) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9798371 | 0.88 | LTA4H (0.54) | NPSR1CYP1A2CYP2C9CYP2C19TEAD1 | |
| SCHEMBL3553556 | 0.87 | LTA4H (0.52) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL27579381 | 0.84 | LTA4H (0.59) | NPSR1CYP1A2CYP2C9CYP2C19TEAD1 | |
| SCHEMBL9546526 | 0.82 | L3MBTL1 (0.55) | NPSR1CYP1A2CYP2C9CYP2C19TEAD1 | |
| SCHEMBL4661 | 0.82 | CA1 (0.57) | NPSR1KIF11ALDH1A1MAPTTSHR | |
| SCHEMBL29824423 | 0.82 | CA1 (0.57) | NPSR1KIF11ALDH1A1MAPTTSHR | |
| SCHEMBL457828 | 0.82 | MAOB (0.54) | ALDH1A1MAPTABCG2MAPK1SLC6A2 | |
| SCHEMBL29623441 | 0.80 | NPSR1 (0.56) | NPSR1CYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-114466839-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2022-05-10 | — | — | CN | disclosed |