Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18010591 | 1.00 | MEN1 (0.41) | MEN1MAPTALOX15ALOX12HBB | |
| SCHEMBL2760314 | 0.84 | MAPT (0.43) | MEN1MAPTKMT2ACDK1CDK2 | |
| SCHEMBL5352352 | 0.81 | MAPT (0.53) | MEN1MAPTALOX15KMT2ACDK1 | |
| SCHEMBL3987697 | 0.81 | ALOX5AP (0.41) | CDK1CDK2TP53ALDH1A1HPGD | |
| SCHEMBL1479429 | 0.78 | POLB (0.53) | ALOX15HSD17B10PIK3C3TP53ALDH1A1 | |
| SCHEMBL5363500 | 0.77 | ALDH1A1 (0.46) | MEN1MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL1479646 | 0.76 | KDM4E (0.48) | MAPTALOX15HSD17B10PIK3C3TP53 | |
| SCHEMBL2367098 | 0.75 | LMNA (0.56) | MEN1MAPTKMT2ATSHRTP53 | |
| SCHEMBL2366644 | 0.75 | POLB (0.44) | MEN1MAPTKMT2AHSD17B10CDK1 | |
| SCHEMBL12240508 | 0.74 | CDK1 (0.46) | MEN1KMT2AHSD17B10CDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |