Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.70 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.70 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.66 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 4/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960673 | 0.85 | NR4A1 (0.72) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL4220632 | 0.85 | NR4A1 (0.72) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL27517502 | 0.84 | EGFR (0.68) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL102983 | 0.83 | RAB9A (0.83) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL2013554 | 0.83 | PARP10 (0.71) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL2686570 | 0.83 | NR4A1 (0.70) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL41220 | 0.83 | NR4A1 (0.70) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL7342141 | 0.83 | NR4A2 (0.70) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL9718167 | 0.83 | NR4A1 (0.70) | NR4A2NR4A1NR4A3MAOBPARP10 | |
| SCHEMBL6830467 | 0.82 | NR4A2 (1.00) | NR4A2NR4A1NR4A3MAOBPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143482-A1 | Pesticidal Substituted Phenylethers | MERIAL LIMITED | 2009-06-04 | — | — | US | disclosed |
| US-20080293824-A1 | Pesticidal substituted piperidines | MERIAL LIMITED | 2008-11-27 | — | — | US | disclosed |
| EP-1879454-A1 | PESTICIDAL SUBSTITUTED PHENYLETHERS | Merial Ltd. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119876-A1 | PESTICIDAL SUBSTITUTED PHENYLETHERS | MERIAL LTD. (GR) | 2006-11-16 | — | — | WO | disclosed |
| EP-0433826-B1 | Fluorophenylpyridines | HOECHST AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| US-5204476-A | For use in chiral tilted smectic liquid crystal phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0288297-B1 | OPTICALLY ACTIVE BENZENE DERIVATIVES AND PROCESS FOR PREPARATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-03-17 | — | — | EP | disclosed |
| EP-0433826-A2 | Fluorophenylpyridines | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-26 | — | — | EP | disclosed |
| US-4985590-A | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0288297-A2 | Optically active benzene derivatives and process for preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293824-A1 | Pesticidal substituted piperidines | ACHE, PNMT, DDT | NR4A2 2856/4885NR4A1 3249/4885NR4A3 2894/4885 |
| US-20090143482-A1 | Pesticidal Substituted Phenylethers | DDT, ACHE, PNMT | NR4A2 2291/4885NR4A1 2776/4885NR4A3 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.