Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.41 |
| ▸ | DRD1 | P21728 | 7/20 | 0.40 |
| ▸ | DRD5 | P21918 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13144727 | 1.00 | LPL (0.41) | LPLLIPGDRD1DRD5DRD2 | |
| SCHEMBL586404 | 0.95 | MAOA (0.46) | LPLLIPGDRD1DRD5DRD2 | |
| SCHEMBL29421599 | 0.95 | MAOA (0.46) | LPLLIPGDRD1DRD5DRD2 | |
| SCHEMBL29623555 | 0.94 | MAOA (0.43) | LPLLIPGDRD1DRD5DRD2 | |
| SCHEMBL586732 | 0.94 | MAOA (0.43) | LPLLIPGDRD1DRD5DRD2 | |
| SCHEMBL29502333 | 0.88 | LPL (0.47) | LPLLIPGBACE1ROCK1 | |
| SCHEMBL16639375 | 0.88 | LPL (0.47) | LPLLIPGBACE1ROCK1 | |
| SCHEMBL13356015 | 0.88 | LPL (0.39) | LPLLIPGBACE1ROCK1 | |
| SCHEMBL5781980 | 0.85 | LPL (0.46) | LPLLIPGBACE1 | |
| SCHEMBL4158988 | 0.85 | LPL (0.44) | LPLLIPGBACE1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |