Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 5/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487234 | 0.84 | PARP1 (0.66) | PARP1GSK3AGSK3BNPC1RAB9A | |
| SCHEMBL3912747 | 0.80 | PARP1 (0.68) | PARP1GSK3AGSK3BNPC1RAB9A | |
| SCHEMBL4151799 | 0.80 | PARP1 (0.51) | PARP1GSK3AGSK3B | |
| SCHEMBL16794593 | 0.79 | NAPRT (0.52) | PARP1GSK3AGSK3BNPC1RAB9A | |
| SCHEMBL13506055 | 0.79 | HPGD (0.62) | KCNMA1NPC1RAB9AALDH1A1HSD17B10 | |
| SCHEMBL18554247 | 0.78 | DHODH (0.58) | KCNMA1NPC1RAB9AALDH1A1 | |
| SCHEMBL3431388 | 0.78 | GAA (0.47) | PARP1GSK3AGSK3BGFERCDC25A | |
| SCHEMBL6826283 | 0.78 | ALDH1A1 (0.50) | GSK3AGSK3BNPC1RAB9ACDC25A | |
| SCHEMBL26623356 | 0.78 | NPC1 (0.59) | NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL27460160 | 0.77 | NPC1 (0.64) | KCNMA1PARP1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2024178404-A | PYRROLE AMIDOPYRIDONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | シャンハイ リンジーン バイオファーマ カンパニー リミテッド | 2024-12-24 | — | — | JP | disclosed |
| EP-3967690-A4 | PYRROLE AMIDOPYRIDONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Ringene BioPharma Co., Ltd. (CN) | 2023-04-12 | — | — | EP | disclosed |
| EP-3967690-A1 | PYRROLE AMIDOPYRIDONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Ringene BioPharma Co., Ltd. (CN) | 2022-03-16 | — | — | EP | disclosed |