Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.51 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.50 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833856 | 0.81 | MAPT (0.58) | DHODHMEN1KMT2AKCNMA1NPSR1 | |
| SCHEMBL14855554 | 0.80 | KMT2A (0.77) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL15183709 | 0.80 | KMT2A (0.77) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL414754 | 0.79 | MEN1 (0.83) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL31053873 | 0.79 | MEN1 (0.83) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL2028671 | 0.79 | DHODH (0.86) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL13506055 | 0.79 | HPGD (0.62) | KMT2AKCNMA1RAB9ANPC1ALDH1A1 | |
| SCHEMBL16404480 | 0.78 | DHODH (0.78) | DHODHMEN1KMT2APKMKCNK2 | |
| SCHEMBL29623640 | 0.78 | KCNMA1 (0.55) | KCNMA1RAB9ANPC1ALDH1A1 | |
| SCHEMBL6246433 | 0.78 | MEN1 (0.86) | DHODHMEN1KMT2APKMKCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337795-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | Femtogenix Limited (GB) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017032983-A1 | PIPERIDINOBENZODIAZEPINE COMPOUNDS WITH ANTI PROLIFERATIVE ACTIVITY | FEMTOGENIX LIMITED (GB) | 2017-03-02 | — | — | WO | disclosed |