Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210686 | 1.00 | PPARD (0.42) | PPARDPPARAPTGER4SLC26A4CYP26A1 | |
| Hydrochloric Acid SCHEMBL1224090 | 0.99 | PPARD (0.41) | PPARDPPARAPTGER4SLC26A4CYP26A1 | |
| SCHEMBL8310811 | 0.91 | PTGER4 (0.42) | PPARDPPARAPTGER4SLC26A4PPARG | |
| SCHEMBL8314225 | 0.89 | SLC26A4 (0.38) | PPARDPPARAPTGER4SLC26A4F2RL3 | |
| SCHEMBL8316517 | 0.89 | BCL2 (0.43) | PTGER4SLC26A4F2RL3KMT2AMEN1 | |
| SCHEMBL8314208 | 0.87 | F2RL3 (0.36) | PTGER4SLC26A4F2RL3KMT2AMEN1 | |
| SCHEMBL9061589 | 0.86 | F2RL3 (0.35) | PPARDPPARAPTGER4SLC26A4F2RL3 | |
| SCHEMBL8310775 | 0.86 | MAOB (0.42) | SLC26A4F2RL3KMT2AHDAC6 | |
| SCHEMBL8311549 | 0.85 | PTGER4 (0.40) | PPARDPPARAPTGER4SLC26A4 | |
| SCHEMBL8310234 | 0.85 | SLC26A4 (0.36) | PTGER4SLC26A4F2RL3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110840847-B | Pharmaceutical compositions for the treatment of cystic fibrosis transmembrane conductance regulator mediated diseases | 沃泰克斯药物股份有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-110713489-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110183440-B | Heteroaryl SYK inhibitors | 勃林格殷格翰国际有限公司 | 2022-04-22 | — | — | CN | disclosed |