Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.40 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.40 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310504 | 0.90 | PTGER4 (0.43) | PTGER4RAPGEF3SLC26A4 | |
| SCHEMBL210686 | 0.85 | PPARD (0.42) | PTGER4SLC26A4PPARDPPARA | |
| SCHEMBL29623656 | 0.85 | PPARD (0.42) | PTGER4SLC26A4PPARDPPARA | |
| SCHEMBL8313568 | 0.84 | CYSLTR2 (0.42) | PTGER4RAPGEF3 | |
| Hydrochloric Acid SCHEMBL1224090 | 0.84 | PPARD (0.41) | PTGER4SLC26A4PPARDPPARA | |
| SCHEMBL8310811 | 0.80 | PTGER4 (0.42) | PTGER4SLC26A4PPARDPPARA | |
| SCHEMBL8314225 | 0.80 | SLC26A4 (0.38) | PTGER4SLC26A4PPARDPPARA | |
| SCHEMBL8310775 | 0.80 | MAOB (0.42) | SLC26A4 | |
| SCHEMBL8316517 | 0.80 | BCL2 (0.43) | PTGER4SLC26A4 | |
| SCHEMBL8314208 | 0.79 | F2RL3 (0.36) | PTGER4SLC26A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |