SCHEMBL29623724

SCHEMBL29623724

O=CCCC(=O)c1cccnc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLOD2 O00469 2/20 0.57
HDAC1 Q13547 2/20 0.55
HDAC8 Q9BY41 1/20 0.55
ALDH1A1 P00352 1/20 0.52
APP P05067 1/20 0.52
GAA P10253 1/20 0.52
HCAR3 P49019 1/20 0.52
HCAR2 Q8TDS4 1/20 0.52
PLOD3 O60568 1/20 0.51
PLOD1 Q02809 1/20 0.51
TBXAS1 P24557 10/20 0.51
CTNNB1 P35222 1/20 0.50
WNT3A P56704 1/20 0.50
F7 P08709 1/20 0.50
F3 P13726 1/20 0.50
SARM1 Q6SZW1 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.50
SIRT6 Q8N6T7 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
SIRT3 Q9NTG7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2560518 1.00 PLOD2 (0.57) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL19043247 0.90 HDAC1 (0.60) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL11917879 0.87 HDAC1 (0.65) PLOD2HDAC1HDAC8TBXAS1TBXA2R
SCHEMBL7075878 0.85 PLOD2 (0.69) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL22978690 0.85 PLOD2 (0.56) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL29450185 0.82 PLOD2 (0.66) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL2693872 0.82 PLOD2 (0.61) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL2638149 0.82 PLOD2 (0.66) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL9199313 0.80 PLOD2 (0.79) PLOD2HDAC1HDAC8ALDH1A1APP
SCHEMBL21133737 0.80 PLOD2 (0.62) PLOD2HDAC1HDAC8ALDH1A1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250347684-A1 METABOLIC BIOMARKERS IN BLOOD SERUM FOR DIAGNOSIS OF ALZHEIMER'S DISEASE UNIV TEXAS (US) 2025-11-13 US claimed
US-20250347684-A1 METABOLIC BIOMARKERS IN BLOOD SERUM FOR DIAGNOSIS OF ALZHEIMER'S DISEASE UNIV TEXAS (US) 2025-11-13 US disclosed
US-20250024877-A1 METHOD FOR EXTRACTION OF TOBACCO FLAVORS FROM AGED TOBACCO LEAVES XERBAL USA LLC (US) 2025-01-23 US disclosed
CN-119060977-A Recombinant nicotine degrading enzyme, preparation method, encoding DNA and application thereof 上海交通大学 2024-12-03 CN disclosed
CN-118252845-A Application of bifidobacterium longum subspecies infantis E4 extracellular polysaccharide 东北农业大学 2024-06-28 CN disclosed
CN-109536466-B Aldehyde dehydrogenase, gene thereof, recombinant bacterium construction and application thereof in furan carboxylic acid synthesis 华南理工大学 2022-04-22 CN disclosed