Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.56 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.54 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450185 | 1.00 | PLOD2 (0.66) | PLOD2NR4A2ALDH1A1GAAAPP | |
| SCHEMBL7075878 | 0.92 | PLOD2 (0.69) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL9199313 | 0.91 | PLOD2 (0.79) | PLOD2NR4A2ALDH1A1GAAAPP | |
| SCHEMBL3939109 | 0.89 | HDAC1 (0.63) | PLOD2TBXAS1HDAC1HDAC8TBXA2R | |
| SCHEMBL3380708 | 0.88 | HDAC1 (0.70) | TBXAS1HDAC1HDAC8TBXA2R | |
| SCHEMBL9466134 | 0.86 | PLOD2 (0.68) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL1987632 | 0.84 | PLOD2 (0.59) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| Niacinamide SCHEMBL28768072 | 0.84 | F7 (0.79) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL5191849 | 0.84 | F7 (0.61) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL9405126 | 0.83 | PLOD2 (0.62) | PLOD2ALDH1A1GAAAPPHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115340525-A | Method for producing and processing synthetic nicotine | 陕西雷曼生物科技有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-113121496-A | Method for preparing bioactive (S) - (-) -nicotine | 刘双红 | 2021-07-16 | — | — | CN | claimed |
| CN-110256403-B | Method for preparing artificial synthetic nicotine | 深圳市馨艺坊生物科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| US-20240245099-A1 | AEROSOL-GENERATING ARTICLE WITH BIOMARKER SENSOR | PHILIP MORRIS PRODUCTS S.A. (CH) | 2024-07-25 | — | — | US | disclosed |
| CN-114276204-B | Preparation method of (S) - (-) -nicotine | 大庆雾泰化工科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117295412-A | Aerosol-generating article with biomarker sensor | 菲利普莫里斯生产公司 | 2023-12-26 | — | — | CN | disclosed |
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | GALAPAGOS NV (BE) | 2023-08-08 | — | — | US | disclosed |
| US-11555818-B2 | Method for the diagnosis and prognosis of cancer | The USA, as represted by the Secretary, Dept. of and Human Services, National Institutes of Health (US) | 2023-01-17 | — | — | US | disclosed |
| WO-2022243270-A1 | MOUTHPIECE WITH CAPILLARY CHANNEL FOR AN AEROSOL-GENERATING DEVICE | PHILIP MORRIS PRODUCTS S.A. (CH) | 2022-11-24 | — | — | WO | disclosed |
| CN-115340525-A | Method for producing and processing synthetic nicotine | 陕西雷曼生物科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114276204-A | Preparation method of (S) - (-) -nicotine | 大庆雾泰化工科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| WO-2001040187-A2 | COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | NIPPON KAYAKU CO., LTD. (JP) | 2001-06-07 | — | — | WO | disclosed |
| CN-1268937-A | Novel compound having effect of promoting neuron differentiation | NIPPON KAYAKU KK (JP) | 2000-10-04 | — | — | CN | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5994540-A | HYDROXY- AND CHLORO-PYRIDYLPYRIDAZINONE DERIVATIVES | LONZA, LTD. (CH) | 1999-11-30 | — | — | US | disclosed |
| US-5760236-A | CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS | LONZA, LTD. (CH) | 1998-06-02 | — | — | US | disclosed |
| US-4342689-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342690-A | HHYPOTENSIVE AGE TS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342691-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4299769-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | ADAMTS1, ADAMTS5, ADAMTS7 | PLOD2 222/4885NR4A2 2820/4885ALDH1A1 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.