Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675609 | 0.84 | MAOB (0.56) | MAOBMAOATSHRAKR1C3RAB9A | |
| SCHEMBL3512311 | 0.82 | TSHR (0.49) | MAOBMAOATSHRALDH1A1KMT2A | |
| SCHEMBL5983772 | 0.80 | AKR1C3 (0.81) | MAOBTSHRAKR1C3RAB9AALDH1A1 | |
| SCHEMBL20337575 | 0.80 | TSHR (0.61) | MAOBMAOATSHRRAB9AALDH1A1 | |
| SCHEMBL1767329 | 0.80 | TSHR (0.65) | MAOBMAOATSHRRAB9AALDH1A1 | |
| SCHEMBL2637757 | 0.79 | TSHR (0.59) | TSHRALDH1A1ALOX15LMNAGRM8 | |
| SCHEMBL2637758 | 0.79 | TSHR (0.59) | TSHRALDH1A1ALOX15LMNAGRM8 | |
| SCHEMBL28865842 | 0.79 | MAOB (0.50) | MAOBMAOATSHRRAB9AALDH1A1 | |
| SCHEMBL791926 | 0.78 | TSHR (0.62) | MAOBMAOATSHRRAB9AALDH1A1 | |
| SCHEMBL27850481 | 0.78 | F2 (0.54) | MAOBMAOATSHRRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113583020-B | JAK2 inhibitor and application | 百极弘烨（广东）医药科技有限公司 | 2022-04-22 | — | — | CN | disclosed |