Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29623809 | 0.84 | MAOB (0.56) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL791926 | 0.82 | TSHR (0.62) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL28865842 | 0.81 | MAOB (0.50) | MAOBMAOATSHRMEN1KMT2A | |
| SCHEMBL1767329 | 0.80 | TSHR (0.65) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL28008405 | 0.79 | TSHR (0.59) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL2036257 | 0.79 | TSHR (0.59) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL8260909 | 0.78 | TSHR (0.54) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL30041959 | 0.78 | TSHR (0.54) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL3721964 | 0.78 | TSHR (0.57) | MAOBMAOATSHRLMNAMEN1 | |
| SCHEMBL924777 | 0.77 | TSHR (0.53) | MAOBMAOATSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1933826-A | Novel pharmaceutical compositions comprising agonists of the thyroid receptor | KAROBIO AB (SE) | 2007-03-21 | — | — | CN | disclosed |