Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970340 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2POLBMCL1HPGDALOX15 | |
| SCHEMBL3394147 | 0.85 | MAPK1 (0.57) | SMN1; SMN2MCL1TDP1RAB9ANPC1 | |
| SCHEMBL1186765 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2POLBHPGDALOX15TDP1 | |
| SCHEMBL5247667 | 0.80 | SMN1; SMN2 (0.71) | SMN1; SMN2POLBHPGDALOX15TDP1 | |
| SCHEMBL20105000 | 0.80 | MCL1 (0.50) | SMN1; SMN2POLBMCL1HPGDALOX15 | |
| SCHEMBL29493662 | 0.80 | MCL1 (0.50) | SMN1; SMN2POLBMCL1HPGDALOX15 | |
| SCHEMBL9773 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2POLBHPGDALOX15TDP1 | |
| SCHEMBL3841381 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2POLBHPGDALOX15TDP1 | |
| SCHEMBL1186533 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2POLBHPGDALOX15TDP1 | |
| SCHEMBL30585275 | 0.79 | SMN1; SMN2 (0.69) | SMN1; SMN2POLBHPGDALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699019-B | Benzofuran derivatives useful in the treatment of central nervous system and other diseases | 华纳巴布科克绿色化学学院有限公司 | 2022-05-10 | — | — | CN | disclosed |