SCHEMBL7970340

SCHEMBL7970340

N#CCC(=O)NCc1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.63
POLB P06746 2/20 0.61
MCL1 Q07820 1/20 0.59
HPGD P15428 4/20 0.58
ALOX15 P16050 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
RECQL P46063 1/20 0.55
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
MAPT P10636 2/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29623938 1.00 SMN1; SMN2 (0.63) SMN1; SMN2POLBMCL1HPGDALOX15
SCHEMBL3394147 0.85 MAPK1 (0.57) SMN1; SMN2MCL1TDP1RAB9ANPC1
SCHEMBL1186765 0.80 SMN1; SMN2 (0.71) SMN1; SMN2POLBHPGDALOX15TDP1
SCHEMBL5247667 0.80 SMN1; SMN2 (0.71) SMN1; SMN2POLBHPGDALOX15TDP1
SCHEMBL20105000 0.80 MCL1 (0.50) SMN1; SMN2POLBMCL1HPGDALOX15
SCHEMBL29493662 0.80 MCL1 (0.50) SMN1; SMN2POLBMCL1HPGDALOX15
SCHEMBL9773 0.79 SMN1; SMN2 (0.69) SMN1; SMN2POLBHPGDALOX15TDP1
SCHEMBL3841381 0.79 SMN1; SMN2 (0.69) SMN1; SMN2POLBHPGDALOX15TDP1
SCHEMBL1186533 0.79 SMN1; SMN2 (0.69) SMN1; SMN2POLBHPGDALOX15TDP1
SCHEMBL30585275 0.79 SMN1; SMN2 (0.69) SMN1; SMN2POLBHPGDALOX15TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2024-06-25 US disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
EP-3621957-B1 FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES AMBIENT PHOTONICS INC (US) 2023-08-23 EP disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2023-05-18 US disclosed
EP-3374354-B1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS AMBIENT PHOTONICS INC (US) 2022-09-28 EP disclosed
CN-108699019-B Benzofuran derivatives useful in the treatment of central nervous system and other diseases 华纳巴布科克绿色化学学院有限公司 2022-05-10 CN disclosed
US-20210082632-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes Ambient Photonics, Inc. (US) 2021-03-18 US disclosed
US-20180346433-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2018-12-06 US disclosed
WO-2018208712-A1 STILBENE AND FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES WARNER BABCOCK INSITUTE FOR GREEN CHEMISTRY, LLC (US) 2018-11-15 WO disclosed
EP-3374354-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS The Warner-Babcock Institute For Green Chemistry LLC (US) 2018-09-19 EP disclosed
WO-2017083488-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS Warner Babcock Institute for Green Chemistry (US) 2017-05-18 WO disclosed
WO-2017083488-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS Warner Babcock Institute for Green Chemistry (US) 2017-05-18 WO disclosed
US-6174877-B1 EXCELLANT BACTERICIDES, ORAL ABSORBABILITY AND STABILITY; IMPROVE THE STABILITY TO RENAL DEHYDROPEPTIDASE I (DHP-I); 2-(2-(N-HETEROCYCLIC-ETHYLTHIO-) DERIVATIVES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-01-16 US disclosed
EP-0876370-A1 CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1998-11-11 EP disclosed
WO-1997025325-A1 CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-07-17 WO disclosed
US-4435407-A ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS; IMMUNOMODULATORS CIBA-GEIGY CORPORATION (US) 1984-03-06 US disclosed
US-4361567-A IMIDAZO(1,5-A)PYRIDINES SCHERING CORPORATION (US) 1982-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12020872-B2 Stilbene and fused stilbene derivatives as solar cell dyes FDFT1, SUN2, CDC73 SMN1; SMN2 4396/4885POLB 2694/4885MCL1 1804/4885
US-20230154691-A1 Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes FDFT1, SUN2, CDC73 SMN1; SMN2 4396/4885POLB 2694/4885MCL1 1804/4885
US-20180346433-A1 BENZOFURAN DERIVATIVES FOR THE TREATMENT OF CNS AND OTHER DISORDERS PMP22, CDR2, CLN6 SMN1; SMN2 27/4885POLB 4080/4885MCL1 3129/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 SMN1; SMN2 4215/4885POLB 2611/4885MCL1 1991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.