Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20746102 | 1.00 | GPR84 (0.44) | GPR84GRM4XDH | |
| SCHEMBL20745317 | 0.89 | GPR84 (0.46) | GPR84GRM4 | |
| SCHEMBL20745662 | 0.83 | GPR84 (0.43) | GPR84GRM4 | |
| SCHEMBL20745659 | 0.83 | GPR84 (0.43) | GPR84GRM4 | |
| SCHEMBL20745696 | 0.83 | GPR84 (0.43) | GPR84GRM4 | |
| SCHEMBL840394 | 0.80 | MAPT (0.50) | GPR84 | |
| SCHEMBL20745071 | 0.72 | XDH (0.44) | XDH | |
| SCHEMBL31695815 | 0.72 | XDH (0.44) | XDH | |
| SCHEMBL20745609 | 0.72 | GPR84 (0.40) | GPR84GRM4 | |
| SCHEMBL20745885 | 0.70 | KDM4E (0.44) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988555-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | AbbVie Inc. (US) | 2022-04-27 | — | — | EP | disclosed |