Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT1A1 | P22309 | 3/20 | 0.81 |
| ▸ | MLNR | O43193 | 1/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.81 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.81 |
| ▸ | CCKAR | P32238 | 1/20 | 0.81 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.81 |
| ▸ | GHSR | Q92847 | 1/20 | 0.81 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.81 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 11/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404435 | 0.95 | UGT1A1 (0.74) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL7404029 | 0.95 | UGT1A1 (0.74) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL7407396 | 0.94 | UGT1A1 (0.73) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL13241242 | 0.93 | UGT1A1 (0.76) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL20455503 | 0.93 | UGT1A1 (0.76) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL20455502 | 0.93 | UGT1A1 (0.76) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL3541917 | 0.91 | UGT1A1 (0.73) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| SCHEMBL3541914 | 0.91 | UGT1A1 (0.73) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| Atazanavir SCHEMBL21565117 | 0.90 | UGT1A1 (1.00) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 | |
| Atazanavir SCHEMBL20629937 | 0.90 | UGT1A1 (1.00) | UGT1A1MLNRNR1I2SLCO2B1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250000821-A1 | METHODS OF USING DIPIVEFRIN | Insignis Therapeutics, Inc. | 2025-01-02 | — | — | US | disclosed |
| CN-111565716-B | Method of using dipivefrin | 因斯格尼斯疗法有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20220193010-A1 | METHODS OF USING DIPIVEFRIN | INSIGNIS THERAPEUTICS INC (US) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250000821-A1 | METHODS OF USING DIPIVEFRIN | QDPR, DNPEP, DPEP1 | UGT1A1 2618/4885MLNR 43/4885NR1I2 4098/4885 |
| US-20220193010-A1 | METHODS OF USING DIPIVEFRIN | QDPR, DNPEP, DPEP1 | UGT1A1 2618/4885MLNR 43/4885NR1I2 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.