Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL188041 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1798863 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL394354 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL12476955 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105736-B | Aluminum-free clean propellant with low burning rate temperature sensitivity coefficient and preparation method thereof | 湖北航天化学技术研究所 | 2025-05-20 | — | — | CN | claimed |
| CN-117645771-A | Solvent-free high-low temperature resistant bulletproof composite matrix resin and preparation method thereof | 上海鑫丰泰新材料科技有限公司 | 2024-03-05 | — | — | CN | claimed |
| CN-117105736-A | Aluminum-free clean propellant with low burning rate temperature sensitivity coefficient and preparation method thereof | 湖北航天化学技术研究所 | 2023-11-24 | — | — | CN | claimed |
| CN-115304757-B | Block type ink resin and preparation method thereof | 成都托展新材料股份有限公司 | 2023-08-11 | — | — | CN | claimed |
| CN-116078555-A | Method for floatation separation of tungsten ore-iron sulfide ore in tungsten ore heating concentration tailings | 中南大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115304757-A | Block type ink resin and preparation method thereof | 成都托展新材料股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-114773760-A | Hard rigid wear-resistant material and preparation method and application thereof | 泉州科牧智能厨卫有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-114395215-A | Sulfone ether epoxy adhesive and UHMWPE fiber reinforced bulletproof composite material and preparation method thereof | 兰溪聪普新材料有限公司 | 2022-04-26 | — | — | CN | claimed |
| US-20220106430-A1 | AMINE CATALYSTS FOR POLYURETHANE FOAMS | HONEYWELL INTERNATIONAL INC. (US) | 2022-04-07 | — | — | US | claimed |
| CN-113860975-A | Safety mixed ignition powder for detonator and preparation method and application thereof | 山西北化关铝化工有限公司 | 2021-12-31 | — | — | CN | claimed |
| US-20090099273-A1 | NON-SILICONE SURFACTANTS FOR POLYURETHANE OR POLYISOCYANURATE FOAM CONTAINING HALOGENATED OLEFINS AS BLOWING AGENTS | HONEYWELL INTERNATIONAL INC. | 2009-04-16 | — | — | US | claimed |
| WO-2009048826-A2 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | HONEYWELL INTERNATIONAL INC. (US) | 2009-04-16 | — | — | WO | claimed |
| US-20090099272-A1 | STABILIZATION OF POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | SOLSTICE ADVANCED MATERIALS US, INC. | 2009-04-16 | — | — | US | claimed |
| CN-1777432-A | Antiviral nucleoside analogs and methods for treating viral infections, particularly HIV infections | UNIV YALE (US) | 2006-05-24 | — | — | CN | claimed |
| EP-1653976-A1 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | YALE UNIVERSITY (US) | 2006-05-10 | — | — | EP | claimed |
| WO-2005011709-A1 | ANTI-VIRAL NUCLEOSIDE ANALOGS AND METHODS FOR TREATING VIRAL INFECTIONS, ESPECIALLY HIV INFECTIONS | YALE UNIVERSITY (US) | 2005-02-10 | — | — | WO | claimed |
| US-20040167096-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | YALE UNIVERSITY | 2004-08-26 | — | — | US | claimed |
| US-5464913-A | Cycloaliphatic epoxy and primary hydroxyl groups-containing cationic resin | KANSAI PAINT CO., LTD. (JP) | 1995-11-07 | — | — | US | claimed |
| US-5405701-A | Storage stability, low temperature curing, electrocoatings | KANSAI PAINT CO., LTD. (JP) | 1995-04-11 | — | — | US | claimed |
| EP-0361334-B1 | Process for making low density flexible polyurethane foams | DOW CHEMICAL CO (US) | 1993-12-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167096-A1 | Anti-viral nucleoside analogs and methods for treating viral infections, especially HIV infections | CCR1, CCR4, CCR3 | CA2 688/4885CA4 396/4885CES1 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.