Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL188041 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL394354 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29624 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1798863 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL457494 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL12476955 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118844448-A | Preparation method of long-acting antibacterial liquid | 孙国明 | 2024-10-29 | — | — | CN | claimed |
| US-11814348-B2 | Oxidizing liquid media for chemical transformations | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-11-14 | — | — | US | disclosed |
| US-11396492-B2 | Direct oxidative amination of hydrocarbons | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-07-26 | — | — | US | disclosed |
| US-11078136-B2 | Oxidation of alkane to alkene | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-08-03 | — | — | US | disclosed |
| US-20210163503-A1 | OXIDIZING LIQUID MEDIA FOR CHEMICAL TRANSFORMATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-03 | — | — | US | disclosed |
| US-10858301-B2 | Direct oxidation of olefins to oxygenated species | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200377448-A1 | DIRECT OXIDATIVE AMINATION OF HYDROCARBONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-03 | — | — | US | disclosed |
| CN-111757866-A | Direct oxidative amination of hydrocarbons | 斯克利普斯研究所 | 2020-10-09 | — | — | CN | disclosed |
| EP-3717454-A1 | DIRECT OXIDATIVE AMINATION OF HYDROCARBONS | The Scripps Research Institute (US) | 2020-10-07 | — | — | EP | disclosed |
| EP-3634926-A1 | OXIDIZING LIQUID MEDIA FOR CHEMICAL TRANSFORMATIONS | The Scripps Research Institute (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3634927-A1 | DIRECT OXIDATION OF OLEFINS TO OXYGENATED SPECIES | The Scripps Research Institute (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3634925-A1 | OXIDATION OF ALKANE TO ALKENE | The Scripps Research Institute (US) | 2020-04-15 | — | — | EP | disclosed |
| US-20200095183-A1 | DIRECT OXIDATION OF OLEFINS TO OXYGENATED SPECIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-03-26 | — | — | US | disclosed |
| US-20200095179-A1 | OXIDATION OF ALKANE TO ALKENE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-03-26 | — | — | US | disclosed |
| CN-110869338-A | Oxidation of alkanes to alkenes | 斯克利普斯研究所 | 2020-03-06 | — | — | CN | disclosed |
| CN-110831916-A | Direct oxidation of olefins to oxygenates | 斯克利普斯研究所 | 2020-02-21 | — | — | CN | disclosed |
| CN-110831917-A | Oxidizing liquid medium for chemical conversion | 斯克利普斯研究所 | 2020-02-21 | — | — | CN | disclosed |
| WO-2018218186-A1 | DIRECT OXIDATION OF OLEFINS TO OXYGENATED SPECIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-11-29 | — | — | WO | disclosed |
| WO-2018218176-A1 | OXIDATION OF ALKANE TO ALKENE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-11-29 | — | — | WO | disclosed |
| WO-2018218171-A1 | OXIDIZING LIQUID MEDIA FOR CHEMICAL TRANSFORMATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163503-A1 | OXIDIZING LIQUID MEDIA FOR CHEMICAL TRANSFORMATIONS | HAO2, LPO, DUOX1 | CA2 143/4885CA4 300/4885CES1 1093/4885 |
| US-20200095183-A1 | DIRECT OXIDATION OF OLEFINS TO OXYGENATED SPECIES | LPO, HAO2, ADH1A | CA2 288/4885CA4 340/4885CES1 787/4885 |
| US-11396492-B2 | Direct oxidative amination of hydrocarbons | GPX4, AOC2, NOX1 | CA2 3243/4885CA4 1265/4885CES1 4457/4885 |
| US-20200377448-A1 | DIRECT OXIDATIVE AMINATION OF HYDROCARBONS | GPX4, AOC2, NOX1 | CA2 3243/4885CA4 1265/4885CES1 4457/4885 |
| US-11078136-B2 | Oxidation of alkane to alkene | LPO, ALK, HAO2 | CA2 93/4885CA4 265/4885CES1 2504/4885 |
| US-10858301-B2 | Direct oxidation of olefins to oxygenated species | LPO, HAO2, ADH1A | CA2 288/4885CA4 340/4885CES1 787/4885 |
| US-11814348-B2 | Oxidizing liquid media for chemical transformations | HAO2, LPO, DUOX1 | CA2 143/4885CA4 300/4885CES1 1093/4885 |
| US-20200095179-A1 | OXIDATION OF ALKANE TO ALKENE | LPO, ALK, HAO2 | CA2 93/4885CA4 265/4885CES1 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.