Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676978 | 0.81 | TDP1 (0.48) | ALDH1A1TSHRTDP1 | |
| SCHEMBL28560981 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| Styrene SCHEMBL490169 | 0.77 | ALDH1A1 (0.93) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| Bromide SCHEMBL60557 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL759390 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL12762137 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9888795 | 0.76 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1HDAC8 | |
| Styrene SCHEMBL26661710 | 0.75 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| Styrene SCHEMBL27916791 | 0.75 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1HDAC8TP53 | |
| SCHEMBL12039386 | 0.74 | ALDH1A1 (0.59) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699206-B | Polymers comprising photoacid generators | 株式会社LG化学 | 2022-05-10 | — | — | CN | disclosed |