Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161047 | 1.00 | NOS3 (0.44) | NOS3NOS2ADRB1MAPK1TAS2R14 | |
| SCHEMBL6163990 | 0.87 | NOS3 (0.35) | NOS3NOS2ADRB1TAS2R14DYRK1A | |
| SCHEMBL810884 | 0.82 | NOS3 (0.61) | NOS3NOS2ADRB1MAPK1CBFB | |
| SCHEMBL30641500 | 0.78 | NOS3 (0.46) | NOS3NOS2ADRB1MAPK1DYRK1A | |
| SCHEMBL30574683 | 0.77 | CCR1 (0.34) | CBFB | |
| SCHEMBL23457557 | 0.77 | METAP2 (0.39) | DYRK1AGSK3BCBFBL3MBTL1 | |
| SCHEMBL29699451 | 0.77 | METAP2 (0.39) | DYRK1AGSK3BCBFBL3MBTL1 | |
| SCHEMBL15624407 | 0.74 | NOS3 (0.53) | NOS3NOS2ADRB1MAPK1DYRK1A | |
| SCHEMBL16964450 | 0.74 | SYK (0.62) | SYK | |
| SCHEMBL5613096 | 0.74 | CCR1 (0.63) | NOS3NOS2ALDH1A1L3MBTL1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368064-B | 1,2, 3-triazole derivative and insecticide and acaricide comprising the same as active ingredient | 北兴化学工业株式会社 | 2022-04-26 | — | — | CN | disclosed |