Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824543 | 0.89 | AR (0.49) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL28782688 | 0.83 | BRD4 (0.47) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL8960942 | 0.83 | FLT3 (0.44) | NPC1RAB9AARKDM4EMAPT | |
| Biphenyl SCHEMBL9470119 | 0.82 | NPC1 (0.57) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL10613155 | 0.81 | AOC3 (0.52) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL9328485 | 0.73 | AOC3 (0.52) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL30990546 | 0.73 | AOC3 (0.52) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL10997076 | 0.72 | NPC1 (0.92) | NPC1RAB9AKDM4EMAPTHPGD | |
| SCHEMBL31465196 | 0.71 | TUBB4A (0.37) | NPC1RAB9AARKDM4EMAPT | |
| SCHEMBL18427579 | 0.71 | AOC3 (0.50) | NPC1RAB9AARKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478354-A | 1, 3-disubstituted indole derivatives as hyaluronidase inhibitor and application thereof in cosmetic products | 北京青颜博识健康管理有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114478354-B | 1, 3-disubstituted indole derivatives as hyaluronidase inhibitor and application thereof in cosmetic products | 北京青颜博识健康管理有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-114478354-A | 1, 3-disubstituted indole derivatives as hyaluronidase inhibitor and application thereof in cosmetic products | 北京青颜博识健康管理有限公司 | 2022-05-13 | — | — | CN | disclosed |