Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | DDO | Q99489 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824543 | 0.85 | AR (0.49) | FLT3DAODDOARAOC3 | |
| SCHEMBL28782688 | 0.83 | BRD4 (0.47) | FLT3PDGFRAPDGFRBARAOC3 | |
| SCHEMBL29624496 | 0.83 | NPC1 (0.50) | FLT3PDGFRAPDGFRBDAOAR | |
| SCHEMBL10613155 | 0.81 | AOC3 (0.52) | FLT3DAODDOARAOC3 | |
| SCHEMBL8960945 | 0.77 | DAO (0.49) | FLT3PDGFRAPDGFRBDAODDO | |
| SCHEMBL9328485 | 0.73 | AOC3 (0.52) | FLT3DAODDOARAOC3 | |
| SCHEMBL30990546 | 0.73 | AOC3 (0.52) | FLT3DAODDOARAOC3 | |
| SCHEMBL18427579 | 0.71 | AOC3 (0.50) | FLT3DAODDOARAOC3 | |
| SCHEMBL6633701 | 0.70 | AOC3 (0.48) | FLT3DAODDOARAOC3 | |
| SCHEMBL8427260 | 0.70 | AOC3 (0.48) | FLT3DAODDOARAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567827-A | 4-Hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-10-22 | — | — | US | disclosed |
| US-5508431-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1996-04-16 | — | — | US | disclosed |
| US-5401855-A | 4-hydroxyphenylthio derivatives, their preparation and their use for the preparation of aminoalkoxyphenylsulphonyl derivatives | ELF SANOFI (FR) | 1995-03-28 | — | — | US | disclosed |