SCHEMBL29625209

SCHEMBL29625209

CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)[C@@H](C)CC)C(C)C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 18/20 0.48
▸ GNPAT O15228 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30092240 0.96 ENPEP (0.49) ENPEPGNPAT
SCHEMBL30680476 0.93 ENPEP (0.46) ENPEP
SCHEMBL29625226 0.90 ENPEP (0.45) ENPEP
SCHEMBL30423080 0.90 NPY4R (0.40) ENPEP
SCHEMBL31206444 0.90 ENPEP (0.47) ENPEPGNPAT
SCHEMBL29777419 0.90 ENPEP (0.48) ENPEPGNPAT
SCHEMBL29604474 0.89 ENPEP (0.44) ENPEPGNPAT
SCHEMBL31022845 0.89 ENPEP (0.50) ENPEP
SCHEMBL29625249 0.89 ENPEP (0.43) ENPEP
SCHEMBL29625204 0.88 NPY4R (0.43) ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220257698-A1 ANGIOTENSIN TYPE 2 (AT2) RECEPTOR AGONISTS FOR USE IN THE TREATMENT OF CANCER LANTHIOPEP B.V. (NL) 2022-08-18 — — US disclosed
CN-114514032-A Angiotensin type 2 (AT2) receptor agonists for the treatment of cancer 兰提欧派普有限公司 2022-05-17 — — CN disclosed
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