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SCHEMBL29625226

SCHEMBL29625226

CC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)CC(=O)O)C(C)C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ENPEP Q07075 12/20 0.45
▸ NPY4R P50391 5/20 0.42
▸ NPY1R P25929 4/20 0.42
▸ NPY2R P49146 4/20 0.42
▸ NPY5R Q15761 4/20 0.42
▸ BACE1 P56817 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29625204 0.98 NPY4R (0.43) ENPEPNPY4RNPY1RNPY2RNPY5R
SCHEMBL29625249 0.96 ENPEP (0.43) ENPEPNPY4RNPY1RNPY2RNPY5R
SCHEMBL29625213 0.92 NPY4R (0.44) ENPEPNPY4RNPY1RNPY2RNPY5R
SCHEMBL29625209 0.90 ENPEP (0.48) ENPEP
SCHEMBL30839890 0.90 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29560353 0.89 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29374977 0.88 NPY4R (0.41) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL29689801 0.88 NPY4R (0.44) ENPEPNPY4RNPY1RNPY2RNPY5R
SCHEMBL31666006 0.87 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5RBACE1
SCHEMBL31394924 0.87 ENPEP (0.55) ENPEPBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220257698-A1 ANGIOTENSIN TYPE 2 (AT2) RECEPTOR AGONISTS FOR USE IN THE TREATMENT OF CANCER LANTHIOPEP B.V. (NL) 2022-08-18 — — US disclosed
CN-114514032-A Angiotensin type 2 (AT2) receptor agonists for the treatment of cancer 兰提欧派普有限公司 2022-05-17 — — CN disclosed
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