SCHEMBL29625266

SCHEMBL29625266

CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(N)=O)C(C)C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 2/20 0.54
▸ OPRM1 P35372 1/20 0.54
▸ OPRD1 P41143 1/20 0.54
▸ NTSR1 P30989 5/20 0.54
▸ NTSR2 O95665 4/20 0.54
▸ SORT1 Q99523 2/20 0.54
▸ F2 P00734 1/20 0.53
▸ REN P00797 5/20 0.53
▸ NMUR2 Q9GZQ4 1/20 0.52
▸ NMUR1 Q9HB89 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30272469 0.89 APLNR (0.58) OPRK1OPRM1NMUR2NMUR1
SCHEMBL30543190 0.88 F2 (0.61) OPRK1OPRM1OPRD1NTSR1NTSR2
SCHEMBL31031539 0.87 CALCR (0.63) OPRK1OPRM1OPRD1
SCHEMBL31031489 0.87 CALCR (0.59) OPRK1OPRM1OPRD1
SCHEMBL30974517 0.87 BACE1 (0.57) OPRK1OPRM1OPRD1NMUR2
SCHEMBL30974520 0.86 BACE1 (0.58) OPRK1OPRM1OPRD1NMUR2
SCHEMBL30512720 0.86 APLNR (0.53) OPRK1OPRM1OPRD1F2
SCHEMBL4541930 0.85 OPRK1 (0.57) OPRK1OPRM1OPRD1NTSR1NTSR2
SCHEMBL30922369 0.85 CALCRL (0.59) —
SCHEMBL30363034 0.85 BACE1 (0.60) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161419-A1 SERPIN PEPTIDES AND METHODS OF USING THE SAME SERPIN PHARMA, LLC 2025-05-22 — — US disclosed
EP-4460322-A2 SERPIN PEPTIDES AND METHODS OF USING THE SAME Serpin Pharma, LLC (US) 2024-11-13 — — EP disclosed
CN-118804758-A SERPIN peptides and methods of use thereof 赛品制药有限责任公司 2024-10-18 — — CN disclosed
US-20240261364-A1 PEPTIDES AND METHODS OF USING THE SAME SERPIN PHARMA, LLC 2024-08-08 — — US disclosed
US-20230406906-A1 SERPIN PEPTIDES AND METHODS OF USING THE SAME SERPIN PHARMA, LLC 2023-12-21 — — US disclosed
US-11779630-B2 Peptides and methods of using the same SERPIN PHARMA, LLC (US) 2023-10-10 — — US disclosed
WO-2023133078-A2 SERPIN PEPTIDES AND METHODS OF USING THE SAME SERPIN PHARMA, LLC (US) 2023-07-13 — — WO disclosed
US-20220265761-A1 PEPTIDES AND METHODS OF USING THE SAME SERPIN PHARMA, LLC 2022-08-25 — — US disclosed
EP-4003391-A2 PEPTIDES AND METHODS OF USING THE SAME Serpin Pharma, LLC (US) 2022-06-01 — — EP disclosed
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