SCHEMBL29625867

SCHEMBL29625867

CCOc1ccc2c(sc3c(F)c(C(F)(F)Oc4cc(F)c(F)c(F)c4)ccc32)c1F

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR2 P21802 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29063206 1.00 FGFR2 (0.31) FGFR2
SCHEMBL29063110 0.90 S1PR1 (0.31) —
SCHEMBL29625874 0.90 S1PR1 (0.31) —
SCHEMBL17355540 0.86 FGFR2 (0.36) FGFR2
SCHEMBL29625860 0.81 — —
SCHEMBL29625873 0.81 — —
SCHEMBL29063204 0.81 — —
SCHEMBL19443983 0.81 RXRA (0.36) —
SCHEMBL17189762 0.81 FAAH (0.33) —
SCHEMBL17189764 0.80 CYP1A2 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263749-A1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES Merck Patent GmbH (DE) 2023-10-25 — — EP disclosed
CN-116670255-A Dibenzofuran and dibenzothiophene derivatives 默克专利股份有限公司 2023-08-29 — — CN disclosed
WO-2022128847-A1 DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2022-06-23 — — WO disclosed
Send feedback