Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799805 | 0.79 | KDM4E (0.59) | LMNAKDM4EMGLLL3MBTL1ALDH1A1 | |
| SCHEMBL8321111 | 0.79 | CYP1A2 (0.65) | KDM4EMGLLL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16004434 | 0.78 | HSP90AA1 (0.59) | KDM4ETDP1HSP90AA1MGLLHSD17B10 | |
| SCHEMBL8319159 | 0.78 | GAA (0.46) | LMNAKDM4EHSP90AA1HSD17B10ALDH1A1 | |
| SCHEMBL10437115 | 0.76 | ALDH1A1 (0.50) | LMNAKDM4ETDP1MGLLALDH1A1 | |
| SCHEMBL2337291 | 0.76 | GSK3A (0.67) | LMNAKDM4EHSD17B10TSHRL3MBTL1 | |
| SCHEMBL14884371 | 0.75 | HSP90AA1 (0.55) | LMNAKDM4ETDP1HSP90AA1MGLL | |
| SCHEMBL11711805 | 0.74 | GSK3A (0.64) | LMNAKDM4EHSD17B10TSHRL3MBTL1 | |
| SCHEMBL9402511 | 0.73 | GSK3A (0.57) | LMNATDP1HSP90AA1MGLLHSD17B10 | |
| SCHEMBL7170106 | 0.73 | GAA (0.44) | LMNAKDM4ETDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423743-A | Triazine derivatives for the treatment of diseases associated with neurotrophic factors | 阿泽克制药公司 | 2022-04-29 | — | — | CN | disclosed |