Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3013325 | 0.84 | GAA (0.59) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29625915 | 0.79 | LMNA (0.50) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8319159 | 0.79 | GAA (0.46) | KDM4EGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL10743256 | 0.78 | KDM4E (0.73) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11834030 | 0.78 | SMN1; SMN2 (0.71) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8883239 | 0.78 | KMT2A (0.63) | KDM4EGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2337291 | 0.77 | GSK3A (0.67) | KDM4EGAAALDH1A1HPGDKMT2A | |
| SCHEMBL9623886 | 0.77 | ALDH1A1 (0.71) | KDM4EGAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9800086 | 0.77 | TP53 (0.58) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8321111 | 0.77 | CYP1A2 (0.65) | KDM4EGAAALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414054-A1 | Hexahydrotriazinetrione containing polyarylenesulfides and process for their preparation | BAYER AG (DE) | 1991-02-27 | — | — | EP | disclosed |