SCHEMBL29626665

SCHEMBL29626665

CCCCOC(=O)Nc1cc([C@H](C)Sc2nncn2C)ccn1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29867346 0.83 CBLB (0.65) CBLB
SCHEMBL29626679 0.82 CBLB (0.69) CBLB
SCHEMBL28741870 0.78 CBLB (0.67) CBLB
SCHEMBL22945356 0.78 CBLB (0.67) CBLB
SCHEMBL29626599 0.78 RAB9A (0.52)
SCHEMBL29866973 0.76 CBLB (1.00) CBLB
SCHEMBL21212719 0.76 CBLB (1.00) CBLB
SCHEMBL21212028 0.76 CBLB (1.00) CBLB
SCHEMBL29867347 0.76 CBLB (1.00) CBLB
SCHEMBL21211993 0.73 CBLB (1.00) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003965-A1 UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION Nurix Therapeutics, Inc. (US) 2022-06-01 EP disclosed