Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.46 |
| ▸ | NOS1 | P29475 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12872 | 0.79 | ROCK2 (0.59) | CDK2HSP90AA1IDO1CTNNB1WNT3A | |
| SCHEMBL29409358 | 0.79 | ROCK2 (0.59) | CDK2HSP90AA1IDO1CTNNB1WNT3A | |
| Bromide SCHEMBL17924434 | 0.78 | ROCK2 (0.57) | CDK2HSP90AA1IDO1CTNNB1WNT3A | |
| SCHEMBL29816258 | 0.76 | NOS1 (0.66) | CDK2HSP90AA1IDO1ROCK2NOS1 | |
| SCHEMBL16573980 | 0.73 | GSK3B (0.71) | CDK2CTNNB1WNT3AROCK2NOS1 | |
| SCHEMBL12354 | 0.71 | KDM4E (0.59) | CDK2HSP90AA1IDO1NOS1MAPT | |
| SCHEMBL20060303 | 0.71 | KDM4E (0.59) | CDK2HSP90AA1IDO1NOS1MAPT | |
| SCHEMBL27537145 | 0.68 | GSK3B (0.64) | ROCK2NOS1MAPTKDM4EALDH1A1 | |
| Indazole SCHEMBL27578122 | 0.68 | HSP90AA1 (0.76) | CDK2HSP90AA1IDO1CTNNB1WNT3A | |
| Indazole SCHEMBL29741164 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260060961-A1 | SUBSTITUTED HETEROCYCLES AS RAS INHIBITORS | JAZZ PHARMACEUTICALS IRELAND LTD (IE) | 2026-03-05 | — | — | US | disclosed |
| WO-2025215188-A1 | THERAPEUTIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PKMYT1 | MY-T BIO LIMITED (GB) | 2025-10-16 | — | — | WO | disclosed |
| WO-2023030385-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-03-09 | — | — | WO | disclosed |
| WO-2022194245-A1 | PYRIMIDINE-FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-09-22 | — | — | WO | disclosed |
| WO-2022161489-A1 | PENTAHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2022-08-04 | — | — | WO | disclosed |
| WO-2022127847-A1 | PYRIMIDONE DERIVATIVE AND APPLICATION THEREOF IN DRUG | 广东东阳光药业有限公司 | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060961-A1 | SUBSTITUTED HETEROCYCLES AS RAS INHIBITORS | KRAS, NRAS, HRAS | CDK2 59/4885HSP90AA1 1830/4885IDO1 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.