Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24539602 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRKMT2AALDH1A1LMNA | |
| SCHEMBL29627391 | 0.85 | MAPT (0.53) | SMN1; SMN2GAAKMT2AALDH1A1LMNA | |
| SCHEMBL29627407 | 0.83 | MAPT (0.50) | TSHRMAPK1GAAKMT2AALDH1A1 | |
| SCHEMBL24539594 | 0.78 | MAPK1 (0.47) | SMN1; SMN2TSHRMAPK1GAAKMT2A | |
| SCHEMBL29627400 | 0.76 | ALDH1A1 (0.52) | MAPK1ALDH1A1LMNAMAPTPKM | |
| SCHEMBL29627403 | 0.76 | NPC1 (0.53) | SMN1; SMN2TSHRMAPK1GAAKMT2A | |
| SCHEMBL29627405 | 0.74 | NPC1 (0.49) | SMN1; SMN2GAAKMT2AALDH1A1RAB9A | |
| SCHEMBL29627393 | 0.74 | HTR1D (0.44) | TSHRMAPK1GAAKMT2ARAB9A | |
| SCHEMBL24539595 | 0.72 | MAPT (0.52) | SMN1; SMN2MAPK1KMT2AALDH1A1LMNA | |
| SCHEMBL24539600 | 0.71 | SETD2 (0.45) | SMN1; SMN2KMT2AALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133058-A1 | RESORCINOL-BASED COMPOUNDS AND USES THEREOF | SUTTER BAY HOSPITALS (US) | 2022-06-23 | — | — | WO | disclosed |