Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29627391 | 0.91 | MAPT (0.53) | NPC1RAB9APOLBMAPTKMT2A | |
| SCHEMBL29627393 | 0.90 | HTR1D (0.44) | NPC1RAB9APOLBMAPTTSHR | |
| SCHEMBL29627399 | 0.88 | MAPT (0.52) | NPC1RAB9APOLBMAPTTSHR | |
| SCHEMBL29627407 | 0.82 | MAPT (0.50) | NPC1RAB9APOLBMAPTTSHR | |
| SCHEMBL27097076 | 0.80 | L3MBTL1 (0.46) | SMN1; SMN2EGFRHTR1A | |
| SCHEMBL24539595 | 0.78 | MAPT (0.52) | NPC1RAB9APOLBMAPTKMT2A | |
| SCHEMBL29627406 | 0.78 | HTR1D (0.46) | MAPTTSHRHSD17B10HPGDTAAR1 | |
| SCHEMBL29627409 | 0.76 | SMN1; SMN2 (0.54) | RAB9AMAPTTSHRKMT2AMAPK1 | |
| SCHEMBL29627400 | 0.75 | ALDH1A1 (0.52) | POLBMAPTMAPK1ALDH1A1EGFR | |
| SCHEMBL29627405 | 0.72 | NPC1 (0.49) | NPC1RAB9AKMT2ATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133058-A1 | RESORCINOL-BASED COMPOUNDS AND USES THEREOF | SUTTER BAY HOSPITALS (US) | 2022-06-23 | — | — | WO | disclosed |