Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20971049 | 1.00 | MAPK9 (0.43) | MAPK9MAPK10ALDH1A1SMN1; SMN2PDPK1 | |
| SCHEMBL20971053 | 0.83 | SRC (0.55) | ALDH1A1SMN1; SMN2PDPK1CA12PARP1 | |
| SCHEMBL19692040 | 0.80 | XDH (0.47) | MAPK9ALDH1A1SMN1; SMN2PARP1IP6K1 | |
| SCHEMBL20971017 | 0.80 | MAPT (0.51) | MAPK9ALDH1A1PARP1SRCMAPT | |
| SCHEMBL20971148 | 0.79 | XDH (0.50) | ALDH1A1SRCMAPTLMNAKMT2A | |
| SCHEMBL29627437 | 0.78 | PARP1 (0.46) | MAPK9ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL20971117 | 0.78 | KMT2A (0.50) | PARP1SRCMAPTLMNAKMT2A | |
| SCHEMBL20971046 | 0.78 | LMNA (0.58) | ALDH1A1PARP1SRCMAPTLMNA | |
| SCHEMBL17868975 | 0.78 | PIM1 (0.46) | MAPK9ALDH1A1SMN1; SMN2PDPK1CA12 | |
| SCHEMBL19692022 | 0.77 | PARP1 (0.46) | MAPK9ALDH1A1SMN1; SMN2PDPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | claimed |
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |