Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29627860 | 0.85 | ROCK2 (0.38) | FFAR1SLC22A12HSP90AB1HAO1 | |
| SCHEMBL29640830 | 0.85 | ROCK2 (0.38) | FFAR1SLC22A12HSP90AB1HAO1 | |
| SCHEMBL25195353 | 0.85 | ROCK2 (0.38) | FFAR1SLC22A12HSP90AB1HAO1 | |
| SCHEMBL25207952 | 0.83 | FFAR1 (0.42) | FFAR1KMT2ASLC22A12MAPTHSP90AB1 | |
| SCHEMBL29627914 | 0.81 | FFAR1 (0.34) | FFAR1PLA2G4A | |
| SCHEMBL29627918 | 0.79 | — | — | |
| SCHEMBL29576192 | 0.76 | KMT2A (0.37) | ALDH1A1KMT2ASLC22A12PLA2G4AMAPT | |
| SCHEMBL26290157 | 0.72 | ROCK2 (0.36) | ACACB | |
| SCHEMBL26289761 | 0.72 | ROCK2 (0.42) | ACACB | |
| SCHEMBL26289720 | 0.71 | ROCK2 (0.38) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003340-A2 | ETHYNYLHETEROCYCLES AS RHO-ASSOCIATED COILED-COIL KINASE (ROCK) INHIBITORS | Angion Biomedica Corp. (US) | 2022-06-01 | — | — | EP | disclosed |