Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640775 | 0.87 | ROCK2 (0.48) | ROCK2ROCK1 | |
| Trifluoroacetic Acid SCHEMBL29627947 | 0.83 | ROCK2 (0.42) | ROCK2ROCK1 | |
| SCHEMBL29640766 | 0.83 | ROCK2 (0.44) | ROCK2ROCK1 | |
| SCHEMBL29640440 | 0.82 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29627927 | 0.81 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29627828 | 0.80 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL29908253 | 0.79 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL29627716 | 0.78 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29627964 | 0.78 | ROCK2 (0.46) | ROCK2ROCK1 | |
| SCHEMBL29627761 | 0.77 | ROCK2 (0.56) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003340-A2 | ETHYNYLHETEROCYCLES AS RHO-ASSOCIATED COILED-COIL KINASE (ROCK) INHIBITORS | Angion Biomedica Corp. (US) | 2022-06-01 | — | — | EP | disclosed |
| CN-114502163-A | Ethynylheterocycles as RHO-related coiled coil kinase (ROCK) inhibitors | 安吉昂生物医药公司 | 2022-05-13 | — | — | CN | disclosed |