Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10727228 | 0.87 | SMN1; SMN2 (0.49) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Acetic Acid SCHEMBL10742452 | 0.85 | SMN1; SMN2 (0.47) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL29508386 | 0.84 | PDPK1 (0.55) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL202156 | 0.84 | PDPK1 (0.55) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Ammonia Solution, Strong SCHEMBL4824906 | 0.83 | PDPK1 (0.53) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Hydrochloric Acid SCHEMBL4766699 | 0.83 | PDPK1 (0.53) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL10427747 | 0.83 | PDPK1 (0.53) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Formic Acid SCHEMBL10727380 | 0.82 | PDPK1 (0.50) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Formic Acid SCHEMBL10738924 | 0.81 | PDPK1 (0.49) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| Quinazolinone SCHEMBL31483770 | 0.81 | PARP1 (0.72) | PARP1SMN1; SMN2PDPK1CA12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312713-B2 | Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors | PFIZER INC. (US) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11312713-B2 | Imidazo[4,5-C]quinoline derivatives as LRRK2 inhibitors | LRRK2, PARK7, BRCA1 | PARP1 647/4885SMN1; SMN2 816/4885PDPK1 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.