Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508386 | 0.98 | PDPK1 (0.55) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| SCHEMBL202156 | 0.98 | PDPK1 (0.55) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4766699 | 0.96 | PDPK1 (0.53) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| SCHEMBL10427747 | 0.96 | PDPK1 (0.53) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Formic Acid SCHEMBL10727380 | 0.88 | PDPK1 (0.50) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Formic Acid SCHEMBL10738924 | 0.87 | PDPK1 (0.49) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Acetic Acid SCHEMBL10727228 | 0.87 | SMN1; SMN2 (0.49) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Acetic Acid SCHEMBL10742452 | 0.85 | SMN1; SMN2 (0.47) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29627985 | 0.83 | PARP1 (0.45) | PDPK1CA12PARP1ALOX15SMN1; SMN2 | |
| Water SCHEMBL10734174 | 0.81 | PDPK1 (0.40) | PDPK1CA12PARP1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610319-B2 | Administering imiquimod | 3M INNOVATIVE PROPERTIES COMPANY | 2003-08-26 | — | — | US | claimed |
| CN-100372847-C | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via novel 1H-imidazo [4,5-C] quinolin-4-cyano and 1H-imidazo [4,5-C] quinolin-4-carboxamide intermediates | TEVA PHARMA (HU) | 2008-03-05 | — | — | CN | disclosed |
| US-7335772-B2 | 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | TEVA GYÓGYSZERGYÁR ZÁRTKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG (HU) | 2008-02-26 | — | — | US | disclosed |
| US-7335772-B2 | 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | TEVA GYÓGYSZERGYÁR ZÁRTKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG (HU) | 2008-02-26 | — | — | US | disclosed |
| EP-1539752-B1 | PREPARATION OF 1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINES VIA NOVEL IMIDAZO[4,5-C]QUINOLIN-4-CYANO AND 1H-IMIDAZO[4,5-C]QUINOLIN-4-CARBOXAMIDE INTERMEDIATES | TEVA GYOGYSZERGYAR ZARTKOERUEE (HU) | 2007-03-21 | — | — | EP | disclosed |
| US-20070060755-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG | 2007-03-15 | — | — | US | disclosed |
| US-7166721-B2 | Preparation of 1H-imidazo[4,5-C] quinolin 4-amines via novel 1H-imidazo[4,5-c] quinolin 4-cyano and 1H-imidazo[4,5-c] quinolin 4-carboxamide intermediates | TEVA Gyógyszergyár Zártkörűen Működő Részvénytársaság (HU) | 2007-01-23 | — | — | US | disclosed |
| US-7153967-B2 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TEVA GYÓGYSZERGYÁR ZÁRTKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG (HU) | 2006-12-26 | — | — | US | disclosed |
| EP-1543002-B1 | PREPARATION OF 1H-IMIDAZO 4,5-C|QUINOLIN-4-AMINES VIA1H-IMIDAZO 4,5-C|QUINOLIN-4-PHTHALIMIDE INTERMEDIATES | TEVA GYOGYSZERGYAR ZARTKOERUEN (HU) | 2006-08-30 | — | — | EP | disclosed |
| CN-1684963-A | Preparation of 1H-imidazo [4, 5-C ] quinolin-4-amines via novel 1H-imidazo [4, 5-C ] quinolin-4-cyano and 1H-imidazo [4, 5-C ] quinolin-4-carboxamide intermediates | TEVA PHARMA (HU) | 2005-10-19 | — | — | CN | disclosed |
| US-20050101627-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4 amines via novel 1h-imidazo [4,5-C] quinolin-4-cyano and 1h-imidazo [4,5-C] quinolin-4-carboxamide intermediates | TEVA PHARAMCEUTICAL INDUSTRIES LTD TO BIOGAL GYOGYSZERGYAR RT. | 2005-05-12 | — | — | US | disclosed |
| US-6852861-B2 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-02-08 | — | — | US | disclosed |
| US-6841678-B2 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via novel 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | BIOGAL GYOGYSZERGYAR RT. (HU) | 2005-01-11 | — | — | US | disclosed |
| US-6780873-B2 | FOR INDUCING CYTOKINE BIOSYNTHESIS IN ANIMALS, AND IN THE TREATMENT OF DISEASES, INCLUDING VIRAL AND NEOPLASTIC DISEASES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20040138459-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2004-07-15 | — | — | US | disclosed |
| US-20040063743-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via novel 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO RESZVENYTARSASAG (HU) | 2004-04-01 | — | — | US | disclosed |
| EP-0802913-B1 | IMIDAZO [4,5-c]QUINOLINE AMINES | MINNESOTA MINING & MFG (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0802913-A1 | IMIDAZO 4,5-c]QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021663-A1 | IMIDAZO[4,5-c]QUINOLINE AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-18 | — | — | WO | disclosed |
| US-5482936-A | INDUCE INTERFERON BIOSYNTHESIS IN AN ANIMAL | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101627-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4 amines via novel 1h-imidazo [4,5-C] quinolin-4-cyano and 1h-imidazo [4,5-C] quinolin-4-carboxamide intermediates | KDM4C, P2RX4, IL4 | PDPK1 1980/4885CA12 3512/4885PARP1 437/4885 |
| US-20070060755-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TLR7, IL4, P2RY4 | PDPK1 2113/4885CA12 3804/4885PARP1 190/4885 |
| US-20040063743-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via novel 1H-imidazo [4,5-c] quinolin-4-cyano and 1H-imidazo [4,5-c] quinolin-4-carboxamide intermediates | IL4, MCM4, CUL4A | PDPK1 2127/4885CA12 3644/4885PARP1 523/4885 |
| US-20040138459-A1 | Preparation of 1H-imidazo [4,5-C] quinolin-4-amines via 1H-imidazo [4,5-C] quinolin-4-phthalimide intermediates | TLR7, IL4, P2RY4 | PDPK1 2154/4885CA12 3757/4885PARP1 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.