SCHEMBL2962835

SCHEMBL2962835

C=C(C)C(=O)OC1CC2C=CC1O2

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPX4 P36969 1/20 0.37
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1088537 0.83 TSHR (0.37)
SCHEMBL7024800 0.78
SCHEMBL8164434 0.78
SCHEMBL3060954 0.70 ALDH1A1 (0.44) GPX4ALDH1A1KDM4ENPC1POLB
SCHEMBL809282 0.68 ALDH1A1 (0.46) GPX4ALDH1A1KDM4ENPC1POLB
SCHEMBL11964233 0.68 ALDH1A1 (0.38) GPX4ALDH1A1KDM4ENPC1POLB
SCHEMBL24486022 0.67 ALDH1A1 (0.46) GPX4ALDH1A1KDM4ENPC1POLB
SCHEMBL16787498 0.67 ALDH1A1 (0.46) GPX4ALDH1A1KDM4ENPC1POLB
SCHEMBL4261488 0.67 ALDH1A1 (0.46) GPX4ALDH1A1KDM4ENPC1POLB
SCHEMBL27209638 0.67 ALDH1A1 (0.41) GPX4ALDH1A1KDM4ENPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1655321-B1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME ZEON CORP (JP) 2012-11-21 EP disclosed
US-7771834-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2010-08-10 US disclosed
US-7666966-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2010-02-23 US disclosed
US-20100015871-A1 MOLDED ARTICLE, PROCESS FOR PRODUCING THE SAME, AND CROSSLINKED MOLDED ARTICLE AND COPPER-CLAD LAMINATE EACH OBTAINED THEREFROM ZEON CORPORATION (JP) 2010-01-21 US disclosed
EP-2067812-A1 MOLDED OBJECT, PROCESS FOR PRODUCING THE SAME, AND CROSSLINKED MOLDING AND COPPER-CLAD LAMINATE EACH OBTAINED FROM THE SAME ZEON CORPORATION (JP) 2009-06-10 EP disclosed
US-20090036614-A1 METHOD OF MANUFACTURING THERMOPLASTIC RESIN, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIAL ZEON CORPORATION 2009-02-05 US disclosed
US-7476716-B2 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2009-01-13 US disclosed
US-7381782-B2 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2008-06-03 US disclosed
EP-1535941-B1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORP (JP) 2007-09-12 EP disclosed
US-20070191563-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2007-08-16 US disclosed
US-20060258828-A1 Polymerizable composition and molded articles produced by using the same ZEON CORPORATION (JP) 2006-11-16 US disclosed
US-20060211834-A1 Method of manufacturing thermoplastic resin, crosslinked resin, and crosslinked resin composite material ZEON CORPORATION (JP) 2006-09-21 US disclosed
EP-1655321-A1 POLYMERIZABLE COMPOSITIONS AND MOLDED ARTICLES PRODUCED BY USING THE SAME Zeon Corporation (JP) 2006-05-10 EP disclosed
EP-1535941-A1 PROCESSES FOR PRODUCING THERMOPLASTIC RESINS, CROSSLINKED RESINS AND CROSSLINKED RESIN COMPOSITE MATERIALS ZEON CORPORATION (JP) 2005-06-01 EP disclosed