SCHEMBL29628587

SCHEMBL29628587

COc1c(Br)ccc(Cl)c1C(C)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NQO2 P16083 1/20 0.33
CHRM2 P08172 6/20 0.32
CHRM1 P11229 6/20 0.32
RRM1 P23921 4/20 0.32
RRM2B Q7LG56 4/20 0.32
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
TSHR P16473 2/20 0.31
PDE2A O00408 1/20 0.31
GLP1R P43220 1/20 0.31
KCNA3 P22001 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
TUBA1B P68363 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20872438 1.00 ALDH1A1 (0.37) ALDH1A1KDM4EHSD17B10NQO2CHRM2
SCHEMBL3842860 0.79 RECQL (0.32) PDE2ACYP2D6
SCHEMBL20872954 0.78 ALDH1A1 (0.38) ALDH1A1KDM4EHSD17B10CHRM2CHRM1
SCHEMBL10209991 0.74 ALDH1A1 (0.45) ALDH1A1KDM4EHSD17B10NQO2ALOX5AP
SCHEMBL3841835 0.74 PDE2A (0.33) PDE2ACYP2D6
SCHEMBL17797225 0.72 L3MBTL1 (0.40) ALDH1A1KDM4EHSD17B10NQO2ALOX5AP
SCHEMBL18560463 0.71 ALDH1A1 (0.47) ALDH1A1KDM4EHSD17B10TSHRTUBB4A
SCHEMBL31045575 0.71 ALDH1A1 (0.38) ALDH1A1KDM4EHSD17B10NQO2ALOX5AP
SCHEMBL30311696 0.70 PDE2A (0.33) PDE2A
SCHEMBL2420963 0.69 CYP1A2 (0.35) ALDH1A1TSHRCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563057-B Sulfonamide compound or salt thereof 大鹏药品工业株式会社 2022-06-24 CN disclosed