Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 4/20 | 0.34 |
| ▸ | EDNRB | P24530 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843687 | 0.81 | NOTUM (0.50) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10547439 | 0.76 | ACLY (0.46) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30027448 | 0.74 | MAPT (0.37) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31438294 | 0.74 | NOTUM (0.33) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19682725 | 0.69 | EPHX2 (0.58) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL532898 | 0.66 | PTGES2 (0.50) | ALDH1A1MAPTTRPV4SLC40A1 | |
| SCHEMBL30731549 | 0.66 | PTGES2 (0.50) | ALDH1A1MAPTTRPV4SLC40A1 | |
| SCHEMBL14907511 | 0.66 | NOTUM (0.60) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9189008 | 0.66 | GAA (0.49) | NOTUMGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29628489 | 0.66 | NOTUM (0.55) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563057-B | Sulfonamide compound or salt thereof | 大鹏药品工业株式会社 | 2022-06-24 | — | — | CN | disclosed |