SCHEMBL2962859

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18038824	0.84	CYP1A2 (0.40)	CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
	SCHEMBL30606887	0.84	CYP1A2 (0.40)	CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
	SCHEMBL3587303	0.81	TDP1 (0.34)	NPSR1MAPTALDH1A1KDM4EGAA
	SCHEMBL21064707	0.75	KDM5A (0.33)	ALDH1A1
	SCHEMBL24638302	0.73	AAK1 (0.39)	CYP1A2CYP2C9CYP2C19MAPTALDH1A1
	SCHEMBL18081244	0.72	MAPT (0.35)	CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1
	SCHEMBL10028356	0.72	MAPT (0.40)	CYP1A2CYP2C9CYP2C19SMN1; SMN2TSHR
	SCHEMBL10710918	0.72	KMT2A (0.40)	CYP1A2CYP2C9CYP2C19MAPTL3MBTL1
	Hydrochloric Acid SCHEMBL25391410	0.72	NPSR1 (0.36)	CYP1A2CYP2C9CYP2C19NPSR1FPR2
	SCHEMBL14908426	0.71	NPSR1 (0.41)	CYP1A2CYP2C9CYP2C19SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.