Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906464 | 0.83 | PIN1 (0.39) | L3MBTL1TSHRKDM4ERAB9APOLB | |
| SCHEMBL17111315 | 0.82 | ALDH1A1 (0.38) | MAPTTSHRKDM4ERAB9APOLB | |
| SCHEMBL28265249 | 0.79 | PIN1 (0.37) | L3MBTL1TSHRKDM4ERAB9APOLB | |
| SCHEMBL27508846 | 0.78 | PIN1 (0.40) | MAPTL3MBTL1TSHRKDM4EPOLB | |
| SCHEMBL6171379 | 0.77 | TBXA2R (0.41) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9460010 | 0.77 | TBXA2R (0.41) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL6209667 | 0.77 | SMN1; SMN2 (0.44) | MAPTRAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2331205 | 0.76 | ALDH1A1 (0.40) | MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL311625 | 0.75 | CYP1A2 (0.46) | MAPTL3MBTL1TSHRKDM4ERAB9A | |
| SCHEMBL311624 | 0.75 | CYP1A2 (0.46) | MAPTL3MBTL1TSHRKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106230-B2 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20100076203-A1 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | DAINIPPON SUMITOMO PHARMA CO., LTD. | 2010-03-25 | — | — | US | disclosed |
| US-4278685-A | DICHLORO-1-PYRROLYLALKANAMIDES, ANTIULCER AGENTS, ANTISECRETORY AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1981-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076203-A1 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation | SUCNR1, DLST, SHMT2 | MAPT 252/4885L3MBTL1 3532/4885TSHR 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.