Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607275 | 1.00 | PDE4D (0.42) | PDE4DMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29628757 | 0.85 | PDE4D (0.40) | PDE4DMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20607103 | 0.85 | PDE4D (0.40) | PDE4DMEN1KMT2ANPC1RAB9A | |
| SCHEMBL20607171 | 0.85 | HTT (0.44) | PDE4DMEN1KMT2ATNFALDH1A1 | |
| SCHEMBL29628740 | 0.85 | HTT (0.44) | PDE4DMEN1KMT2ATNFALDH1A1 | |
| SCHEMBL23456412 | 0.77 | ALDH1A1 (0.40) | PDE4DMEN1KMT2ATNFALDH1A1 | |
| SCHEMBL20607466 | 0.76 | PDE4A (0.40) | PDE4DTNFALDH1A1MAPTLMNA | |
| SCHEMBL29628796 | 0.76 | PDE4A (0.40) | PDE4DTNFALDH1A1MAPTLMNA | |
| SCHEMBL20607092 | 0.75 | CLCN2 (0.41) | PDE4DALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL29628651 | 0.75 | CLCN2 (0.41) | PDE4DALDH1A1MAPTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |