Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144878 | 0.86 | CYP2A6 (0.59) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 | |
| SCHEMBL10371842 | 0.77 | CYP2A6 (0.56) | CYP2A6PDE10ASIGMAR1CA2CA12 | |
| SCHEMBL1774025 | 0.73 | CYP2A6 (0.66) | CYP2A6PDE10ASIGMAR1CA2CA12 | |
| SCHEMBL4057654 | 0.73 | CYP2A6 (0.51) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 | |
| SCHEMBL10030470 | 0.73 | CYP2A6 (0.47) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 | |
| SCHEMBL3145920 | 0.73 | MRGPRX4 (0.43) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 | |
| SCHEMBL5547137 | 0.72 | CYP2A6 (0.54) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 | |
| SCHEMBL10368304 | 0.71 | SIGMAR1 (0.51) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 | |
| SCHEMBL3789042 | 0.70 | CYP2A6 (0.61) | CYP2A6PDE10ASIGMAR1CA2CA12 | |
| SCHEMBL2091182 | 0.70 | CYP2A6 (0.61) | CYP2A6PDE10ASIGMAR1MRGPRX4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445249-B1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7772285-B2 | Benzophenone derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-08-10 | — | — | US | disclosed |
| EP-1445249-A1 | NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-08-11 | — | — | EP | disclosed |