Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607117 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL13554474 | 0.92 | ALDH1A1 (0.50) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL20607035 | 0.89 | ALDH1A1 (0.46) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL23202773 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL31063093 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPK1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL20607231 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29628684 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31359168 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1KMT2AMEN1CYP1A2 | |
| SCHEMBL1515834 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL31714770 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPK1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |