Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607231 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPK1ALDH1A3MAPTLMNA | |
| SCHEMBL13554474 | 0.89 | ALDH1A1 (0.50) | ALDH1A1MAPK1ALDH1A3MAPTLMNA | |
| SCHEMBL23202773 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPK1MAPTLMNAHPGD | |
| SCHEMBL31063149 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTHPGDHSD17B10 | |
| SCHEMBL5759025 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MAPK1MAPTHPGDHSD17B10 | |
| SCHEMBL29628744 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1ALDH1A3MAPTLMNA | |
| SCHEMBL20607117 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPK1ALDH1A3MAPTLMNA | |
| SCHEMBL31359168 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPK1MAPTLMNAHPGD | |
| SCHEMBL1515834 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MAPK1MAPTLMNAHTT | |
| SCHEMBL27163794 | 0.78 | HTR2A (0.33) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |