SCHEMBL29628752

SCHEMBL29628752

O=C1C(Cl)Oc2c(cccc2S(=O)(=O)Cl)N1CC(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29628441 0.76 HTR6 (0.31)
SCHEMBL29628564 0.63 DRD2 (0.32)
SCHEMBL19682915 0.61 CHRM2 (0.49)
SCHEMBL31387044 0.60 GRM2 (0.36)
SCHEMBL27037012 0.60 GRM2 (0.36)
SCHEMBL27036993 0.57 SMN1; SMN2 (0.43) MEN1KMT2A
SCHEMBL28868740 0.54 PARP1 (0.33) KMT2A
SCHEMBL464779 0.54 GSK3B (0.42)
SCHEMBL1515862 0.53 PTGES2 (0.46)
SCHEMBL29543283 0.53 PTGES2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563057-B Sulfonamide compound or salt thereof 大鹏药品工业株式会社 2022-06-24 CN disclosed